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Liver Tumours (Hepatocellular Carcinoma (Clinical Presentation (Jaundice,…
Liver Tumours
Hepatocellular Carcinoma
Pathophysiology
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It can metastasise via the hepatic or portal veins to the lymph nodes, bones and lungs
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Clinical Presentation
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On examination an enlarged, irregular, tender liver may be felt
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Risk Factors
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Associated with cirrhosis such as alcohol cirrhosis, non-alcoholic fatty liver disease and haemochromatosis
Diagnosis
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Enhanced CT - to identify HCC but hard to confirm diagnosis if the lesion is less than 1cm & usually used to confirm diagnosis if lesion is large enough
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Liver biopsy - under ultrasound guidance to confirm diagnosis, used less now due to potential seeding of tumour along biopsy tract and since imaging is better
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Secondary Liver Tumours
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Treatment
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Chemotherapy is used, particularly with breast cancer
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Epidemiology
Particularly from: GI tract, breast and bronchus
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Haemangioma
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Usually found on ultrasound, CT or MRI and have characteristic appearances
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Hepatic Adenoma
Associated with oral contraceptives, anabolic steroids and pregnancy
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Surgical resection is only required for symptomatic patients with tumours larger than 5cm in diameter