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L13 Mechanisms of gastric acid secretion and their control, stomach wall…
L13 Mechanisms of gastric acid secretion and their control
stomach wall
comprised of tissue layers
mucosa
fundic region
of the mucosa
gastric mucosal cells
:check:gastric parietal cells
secret
Acid (HCl)
:star:Hydrochloric acid secretion
Gastric Mucosal Barrier
2 more items...
Cellular Mechanism
2 more items...
:check:Digestive secretions
Parietal Cell Structure
Huge membrane surface area
A canaliculus with or w/o microvilli
Intracytoplasmic tubulovesicles
Dense with mitochondria
A membrane linked H/K ATPase (proton) pump
Carbonic anhydrase
:check:chief cells
secret
Pepsinogen (Activated by low pH --> pepsin)
gastric mucosa structure
specialized
for secretion
fundic region
:check:surface mucous cell & mucous neck cells
secret
Mucus
submucosa
circular and longitudinal
muscle layers
peritoneum
