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transcription (1. transcription initiation (holoenzyme: core enzyme +…

- - - - RNA polymerase encounters a G-C rich region which causes the strand to base pair with itself and form a 'hairpin'; the RNA snaps together and pulls out of the complex, as the DNA strands rewind together
      - GC-rich region causes strand to base pair with itself
        
        RNA snaps together
        
        pulls out of complex
        
        DNA strands rewind together
    - - GC-rich sequence causes RNA polymerase
        to pause
        
        Rho protein catches up
      - Rho protein travels along the mRNA strand until it catches up to the RNA polymerase and unwinds the DNA-RNA hybrid, releasing the new mRNA strand