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COVID19 strategies (Broad Spectrum (pH-dependent (Chloroquine phosphate…

- - - - Camrelizumab & thymosin
    - - Tocilizumab
      - sarilumab
    - - IFX-1
  - - - CR3022
    - - https://www.medrxiv.org/content/10.1101/2020.03.17.20037713v1.full.pdf
  - - - Import blood samples from asia? Contact blood bank in Japan and have samples from recovered individuals sent along with shipment of over samples to help reduce costs.
      - Local recoveries (although currently very scarce, but expected to increase exponentially)
  - - - 90% similarity between SARS-CoV & SARS-CoV2
      - N ELISA was more sensitive than S1 ELISA
  - - - Oral swabs better suited for early phase detection and anal swabs for late phase detection
- - - - Similar approach to that of Medicago in collaboration with Lavals University's Infectious Disease Research Centre
- - - - https://www.cell.com/cell/fulltext/S0092-8674(20)30229-4
  - - - https://www.nature.com/articles/d41587-020-00003-1
    - - darunavir & cobicistat
- - - - https://www.sciencedirect.com/science/article/pii/S0924857920300881
- - - - favipiravir (influenze drug that didn't show strong activity)
      - Phosphoramidate prodrug
      - ribavirin
      - pyrazofurin
    - - Baloxavir marboxil
- - - - lateral flow assays
        
        https://www.fda.gov/media/136625/download
        
        Detects IgG and IgM
        
        https://pharmact-health.com/en/sars-cov-2-rapid-test/
        
        99.8% sensitivity for 272 negative controls
        
        70% compliance for early stage (4-10 days)