Please enable JavaScript.
Coggle requires JavaScript to display documents.
lymphatic/immune system (immunity (innate defenses (-surface barriers skin…
lymphatic/immune system
immune system
Innate immunity
-non-specific immunity
-body's first natural defense
-first defense: skin & mucous lining
Adaptive immunity
-components: T lymphocytes & B lymphocytes
- B cells make antibodies
Luekocytes
-neutrophils
-macrophages
-dendritic cells
lymphatic system
-lymph nodes : cleanse lymph, site for lymphatic activation
-spleen: cleanses blood & removes defective blood cells
-MALT: Prevent pathogens from penetrating mucous membrane
lymphatic transport
-low pressure conducts, usually bundled together
-lymph transport is sporadic & slow
-Functions:
-return excess tissue fluid to the blood, return leaked proteins to the blood, carry pathogens to lymph nodes, carry absorbed fat from intestine to the blood
lymphoid tissues
-houses lymphocytes & provides a site where they can be activated & multiplied
-composed of loose connective tissue & reticular connective tissue
-dominates lymphoid organs except the thymus
lymph node
-tabeculae: dense fibrous capsule from which connective tissue strands
-cortex: superficial cortex has packed follicles with dividing B cells
-deeper cortex houses T cells in transit
-medulla: Both B and T lymphocytes are found here
-lymph sinuses: large lymphatic capillaries
Circulation
-lymph enters lymph node through efferent lymphatic vessels
-then moves through the subcapsularsinus into many smaller sinuses that cut through the cortex and enter medulla
-lymph travels through medualary sinuses and then exits the node at its hilum through efferent lymphatic vessels
-
-
immunity
innate defenses
-surface barriers skin & mucous membrane
-internal defenses: phagocytes, natural killer cell, inflammation, & antimicrobial proteins, fever
-
-
Humoral immunity
-anitbodies produced by lymphocytes
-blind temporarily to target cells
circulate freely in body fluids
cellular immunity
-lymphocytes act against target cells
-directly by killing infected cells
-indirectly by releasing chemicals
-cellular immunity has cellular targets
Antigen
-antigens: substances that can mobilize adaptive defenses & produce immune responses
-targets of all adaptive immune response
-most are large, complex molecules not normally found in the body
characteristics can be a self antigen