Until now, several approaches have been tested to dissolve cured barnacle cement (Barnes and Blackstock, 1976; Naldrett, 1993; Kamino et al., 1996, 2000; Naldrett and Kaplan, 1997; Wiegemann et al., 2006; So et al., 2016), two of which show promising results. The first employs high concentrations of denaturants and reductants that are paired with a heat treatment. This method can render more than 90% ofM. rosa cement soluble and release barnacle individuals directly from the substrate (Kamino et al., 2000) .... The second method relies on only one polar solvent, hexafluoroisopropanol, to break down hydrogen bonds important for the stabilization of amyloid fibers. Using this reagent, So et al. (2016) dissolved [Liang et al., 2019].