Please enable JavaScript.

Coggle requires JavaScript to display documents.

Defense mechanisms (Nonspecific (1st line (mucous membrane (digestive,…

- - - - Cellular
        
        platelets
        
        leukocytes
        
        granulocytes
        
        eosinophils
        
        neutrophils
        
        basoohils
        
        agranulocytes
        
        lymphocytes
        
        monocytes
        
        Erythrocytes
        
        all blood cells came from a pluripotent stem cell in the bone marrow
        
        becomes myeloid stem cell
        
        Inflammation
        
        basophils
        
        phagocytosis
        
        neutrophils
        
        eosinophils
        
        monocytes
        
        critical link between the 2nd and 3rd line communications
        
        can also differentiate into macrophages
        
        2 more items...
      - Fluid
        
        plasma
        
        serum
    - - 5 stages
        
        ingestion
        
        digestion
        
        adherence
        
        elimination
        
        Chemotaxis
      - MHC (major histocompatibility complex) prevent self-digestion
    - - acute
      - chronic
      - inflammatory response
        
        diapedesis
        
        antimicrobial chemicals and clotting factors
        
        vasodilation, vessels more permeable to macrophage
        
        blood clot forms
        
        damaged cells release prosta-glandin, histamines, other signaling molecules
        
        more phagocytes migrate over
        
        portal of entry created
        
        damaged tissue forms pus, repaired by undifferentiated stem cells
    - - does NOT inhibit growth of microbe
        
        enhances performance of all lines of defence
      - pyrogen
        
        antibody-antigen complex
        
        Interleukin-1
        
        increase in core body temperature
    - - complement system
        
        set of 15 serum proteins that tag, promote, poke holes in microbe
        
        cellular, extracellular pathogens
      - interferon system
        
        antiviral proteins (AVP)
        
        flu-like symptoms are caused by these interferons
        
        cells cannot be cured from a virus, only apoptosis to get rid of it and the cell must die in the process
        
        Viral, intracellular pathogens
  - - - digestive
      - urogential
      - Respiratory
    - - Lysozyme
    - - Perspiration
      - Sebum
    - - normal flora