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Lymphatic/Immune System (Major Function of the Lymphatic & Immune…
Lymphatic/Immune System
Major Function of the Lymphatic & Immune Systems
Lymphatic System
Returns clean fluids and peak proteins back to the blood
Drains excess fluid from tissue
Play an essential role in body defenses and resistance to diseases
Immune System
A collection of structures and processes within the body which is used to protect against disease or other potentially damaging foreign bodies.
Consists of:
White blood cells
Phagocytes & Lymphocytes
Bone Marrow
Lymph Nodes
Thymus
Spleen
Anatomy of the Lymphatic System (Including Vessels, Nodes, MALT, Spleen, & Thymus)
Innate/Natural Immune Defenses and Adaptive/Acquired Immune Defenses
Humoral vs. Cellular Response
Humoral Response
Also known as Antibody-meditated immunity
Antibodies defend against infection in body fluids
Lymphocytes that mature in the bone marrow are called B cells and are involved in the humoral immune response
Both B and T cells have receptor proteins to bind to antigens
Each individual lymphocytes are designed to recognize to a specific type of antigen
Cellular Response
Aldo called the cell-meditated immunity
Cytotoxic cells defend against infection in already infected, cancer, or transplanted cells
Lymphocytes that mature in the thymus are celled T-cells and are involved in the cell-meditated immune response
Antigens and Antibodies
Antibody
Also known as immunoglobulin or Ig
Soluble protein secreted by the plasma cells derived from the B cells
Carried in body fluids
Capable of binding specifically to antigens
Structure of the Antibody
Made of four amino acid chains linked by a disulfied bond
Two light chains
Two heavy chains are made by two identical amino acids are linked together
Two variable region makes up the antigen binding site
Antigen-binding site is specific to the antigen
Constant portion is same to all antibodies
Antigen
Disorders of the Immune System