CHAPTERS 42 AND 44

Circulation and Gas Exchange (Ch42)

Osmoregulation and Excretion (Ch44)

Osmosis

Hopoosmotic side: lower solute concentration, higher free water concentration

Net water flows from hypoosmotic side to hyperosmotic side

Water enters and leaves cells by osmosis

Occurs when two solutions separated by a membrane differ in total solute concentration

Hyperosmotic side: higher solute concentration, lower free water concentration

The diffusion of free water across a selectively permeable membrane

Marine vs Freshwater animals

Osmolarity of marine animals is the same as that of seawater, so they face no substantial challenges in water balance

Osmolarity of freshwater animals is higher than that of their surroundings, they face the problem of gaining water by osmosis

Marine: excrete salt ions and small amounts of water in scanty urine from kidneys

Freshwater: excrete salt ions and large amounts of water in dilute urine from kidneys

Freshwater: drink almost no water

Marine: gain of water and salt ions from drinking seawater

Freshwater: osmotic water gain through gills and other parts of body surface

Marine: Osmotic water loss through gills and other parts of body surface

Freshwater: uptake of salt ions by gills

Marine: excretion of salt ions from gills

Nitrogenous wastes

Ammonia

animals need access to lots of water because ammonia can be tolerated only at very low concentrations

many invertebrates, most aquatic animals, including most bony fishes

Urea

mammals, most amphibians, sharks, some bony fishes

Urea is less toxic than ammonia for land animals

urea is the product of an energy-consuming metabolic cycle that combines ammonia with CO2 in the liver

Uric acid

birds and many other reptiles, insects, land snails

ric acid can be excreted as a semisolid paste with very little water loss

Excretory organs

Kidneys: functions in osmoregulation and excretion; organs for transporting and storing urine

Ureters: carry urine from kidneys to bladders

Urinary bladder: receive urine from ureters and store urine

Urethra: during urination, urine is expelled from the bladder through urethra; in males, this is a path for sperms

Sphincter muscles near the junction of the urethra and bladder regulate urination

Nephron

Bowman's capsule: Collects the incoming fluid from the glomerular capillaries.

Proximal tubule

Sodium, chloride, water, glucose and amino acids are reabsorbed (removed from the tubules).

Organic acids and bases like bile salts, oxalate and urate are secreted into the proximal tubule.

Loop of Henle

Water is reabsorbed mainly in the descending limb and thin segment of the ascending limb.

Sodium, calcium, chloride, magnesium and potassium are actively reabsorbed in the thick segment of the ascending limb.

Distal tubule

Controls the blood flow through the glomerular capillaries and glomerular filtration of the nephron to which it belongs.

Sodium, potassium and chloride reabsorption.

Collecting tubule

Sodium, potassium and chloride reabsorption.

Hydrogen ion secretion.

Circulatory system

Open circulatory systems

Circulatory fluid: hemolymph bathing the body cells

Arthropods such as grasshoppers, and some molluscs including clams

Heart pumps the hemolymph through the circulatory vessels into interconnected sinuses, spaces surrounding the organs

Hemolymph and body cells exchange gases and other chemicals within the sinuses

Pores have valves that close when the heart contracts

Relaxation of the heart draws hemolymph back in through pores

Body movements squeeze the sinuses, helping circulate the hemolymph

Closed circulatory system

Circulatory fluid: blood is confined to vessels and is distinct from the interstitial fluid

Annelids (including earthworms), cephalopods (including squids and octopuses) and all vertebrates

Heart(s) pumps blood into large vessels that branch into smaller ones that infiltrate the tissues and organs

Chemical exchange occurs between the blood and the interstitial fluid, between interstitial fluid and body cells

no arteries to increase bp, so there's more blood at low pressure

requires less energy for distributing blood

blood remains within a network of vessels and doesn't leave

carries blood at high pressure and delivers blood quickly

suitable for animals with fast metabolism, be able to move, digest and eliminate waste quickly

Single circulation

Blood flows through heart only once for completing one circulation

pulmonary circulation is absent

2 chambered heart

fish

one atrium, one ventricle

the heart draws in deoxygenerated blood in a single atrium and pumps it out of ventricle

Double circulation

three or four chambered heart

having both pumps within a single heart simplifies coordination of the pumping cycles

amphibians, reptiles and mammals

pathways that enable the blood to flow from the heart to lungs and return back to the heart for systematic circulation

right side, heart pumps oxygen-poor blood to the capillary beds of the gas exchange tissues, O2 into blood and CO2 out of blood

left side, heart pumps oxygen-enriched blood from the gas exchange tissues to capillary beds through out the body

following the exchange of O2 and CO2, nutrients and waste products, the oxygen-poor blood returns to the heart

Types of hearts

2-chambered hearts

fish

one atrium, one ventricle

one single loop

blood goes to the gill to get oxygen, then it goes to the body and then goes back to the heart

2 chambers are separated by a valve

3-chambered hearts

amphibians

two atrial and one ventricle

two loops

one loop goes to the lungs and comes back to the heart

one loop goes to the rest of the body

4-chambered hearts

birds and mammals

2 atria, 2 ventricles

double loops

The atria are the two upper chambers that receive blood from the veins

The ventricles are the two lower chambers that pump blood into the arteries.

The heart can be described as two separate pumps, a left pump and a right pump.

arteries, veins, capillaries

Arteries

no valves

blood speed fast

high pressure with thicker wall

from heart to the rest of the body

carry mostly oxygenated blood

Veins

from the rest of the body to heart

carry mostly deoxygenated blood

low pressure with thinner walls

have valves

blood speed slow

capillaries

connect arteries and veins

carry both blood

walls only one cell thick for diffusion

no valves

Blood pressure

Blood pressure is the force that is exerted against arteries when blood flows through

systolic pressure: measures the pressure in the arteries when the heart muscle contracts

diastolic pressure: measures the pressure in the arteries when the heart is at rest

HBP occurs when the artery walls become less elastic, allowing fat to build up against the walls and prevents blood to get through

LBP (hypotension) means that the heart isn’t pumping as much blood to the body as it should, leading to a lack in O2

HBP is dangerous, the heart works harder to pump blood out to the body and helps hardern the arteries, or atherosclerosis, to stroke, kidney disease, and to heart failure.

when bp is recorded, first number is systolic pressure, second is diastolic

bp is measured for an artery in the arm at the same height as the heart

vasoconstriction: process when the smooth muscles in arteriole walls contract, the arterioles narrow

vasodilation: an increase in diameter that causes bp to fall when smooth muscles relax

Lymph circulation

fluid and proteins leak from the blood capillaries into the interstitial fluids

supporting role for cardiovascular and immune system

maintains homeostasis

lymph: watery fluid flows through lymphatic system; recovery fluid

valves in larger lymphatic vessels prevent in the backflow of fluid

lymph nodes: lymph-flitering organs play an important role in body's defense

lymphatic vessels recover leaked fluid and proteins, carrying them to large veins at the base of the neck

when body fights an infection, wbc multiplies rapidly, lymph nodes become swollen and tender

lymphatic system plays a role in harmful immune responses

Blood

made up of red blood cells, white blood cells, plasma, platelets

RBC: carrying oxygen around the body

Plasma: liquid portion, has a lot of nutrients, carrying CO2 as bicarbonate

WBC: fight infection

Platelets: important in blood clotting

Supply of oxygen to tissues (bound to hemoglobin, which is carried in red cells)

Supply of nutrients such as glucose, amino acids, and fatty acids (dissolved in the blood or bound to plasma proteins

plasma transports substances needed by cells and removes wastes and products from cells

Normal blood pressure is considered 120/70

heart attack: is the damage or death of cardiac muscle tissue resulting from blockage of coronary arteries

stroke: death of nervous tissue in the brain due to a lack of O2

hypertension:chronic hbp damages the endothelium that lines the arteries, promoting plaque formation

hypertension: systolic pressure above 140 mm Hg or diastolic pressure above 90 mmHg

Respiratory organs

55% plasma, 45 cellular elements

Respiratory surfaces

cells carrying out gas exchange have a plasma membrane must be in contact with an aqueous solution

movement of O2, and CO2 across respiratory surfaces takes place by diffusion

respiratory surfaces tend to be large and thin

rate of diffusion is proportional to the surface area

some relatively simple animals like sponges, cells in the body is close to the external environment that gases can diffuse

surfaces is moist epithelium that constitutes a respiratory organ

earthworms, and some amphibians and other animals, skin serves as a respiratory organ

network of capillaries below skin facilitates the exchange of gases between circulatory system and environment

Gills (aquatic animals)

outfoldings of the body surface that are suspended in water

total surface area much greater than that of the rest of the body's exterior

ventilation: maintains the partial pressure gradients of O2, CO2 across the gill that are needed for gas exchange

Countercurrent exchange: exchange of a substance/heat between 2 fluids flowing in opposite directions (blood and water)

gill provides a surface where water (dissolve O2) comes into contact with the blood of the fish

diffusion: O2 will flow from water into blood

Tracheal systems in insects

respiratory surfaces are enclosed within the body, exposed to the atmosphere through narrow tubes

network of air tubes that branch throughout the body

largest tube, tracheae, open to the outside

a moist epithelial lining enables gas exchange by diffusion at the tips of the finest branches

branch to form tracheoles that reach every cell

Lungs

lungs are are localized respiratory organs

an infolding of the body surface, subdivided into numerous pockets

circulatory system transports gases between the lungs and the rest of the body

evolved both in organisms with open circulatory system, such as spiders and land snails, and vertebrates

most reptile and all mammals depend on lungs for gas exchange

turtles: lung breathing with gas exchange across moist epithelial surfaces continuous with their mouth or anus

human lung contains millions of alveoli - air sacs clustered at the tips of the tiniest bronchioles

bronchiole: a fine branch of the bronchi that transports air to alveoli

in mammals, air inhaled through the nostrils passes through the pharynx into trachea, bronchi, bronchioles and alveoli

if lungs are present in amphibians, they are super small

Breathing

positive pressure: forces air down the trachea

negative pressure: pulls air into the lungs when rib muscles and diaphragm contract

amphibian ventilates its lungs by positive pressure breathing

birds use a system of air sacs as bellows to keep air flowing through the lungs in one direction

mammals ventilate their lungs by negative pressure

negative breathing: incoming and outcoming air mix, decreasing efficiency of ventilation

rib cage expands/gets smaller as rib muscles contract/relax

diaphragm: most important; a sheet of skeletal muscle that forms the bottom wall of the cavity

inhalation: active, exhalation: passive

diaphragm: inspiration; when it contracts, it flattens out, increasing volume inside the lung

innervation: phrenic nerve

external intercostal: allows ribs to move

internal intercostal: draws the ribs together and depress the rib cage