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Acute Coronary Syndrome (Pathophysiology of ACS (Stable Angina (Normal ECG…
Acute Coronary Syndrome
Pathophysiology of ACS
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Stable Angina
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During Exercise, 50% reduction of the lumen leads to symptoms
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Unstable Angina
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Platelet accumulation and transient episodes of thrombotic occlusion may cause by the atherosclerotic plaque fissures
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Histopathology of ACS
Atherosclerosis
Accumulation of immune, inflammatory, smooth muscle cells, lipids, and connective tissue in Tunica Intima
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AMI Histology
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3 days - 1 week
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Micro
Nuclei disappear, accumulation of inflammatory cells
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Treatment and Management
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Treatment
Inital
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Aspirin
Clopidogrel, to protect the heart from further insult, it can prevent blood clots
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Pathophysiology of Angina, STEMI and NSTEMI
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