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You are assigned to care for a 34-year old male patient recently diagnosed…

- - - - strep throat
      - antibiotic treatment
        
        antibiotic drugs can usually kill bacteria
      - not contageous
    - - AIDS
      - common colds
      - contageous
      - cannot be treated with antibiotics
        
        antibiotics not effective against viruses
    - - contaninated surfaces
      - infected pets/animals
      - sneezing
      - coughing
  - - - seeding secondary lymphoid organs
        
        immunocompetent but still naive lymphcytes leave thymus and bone marrow
        
        seed the secondary lymphoid organs and circulate though blood and lymph
      - antigen encounter and activation
        
        lymphocytes antogen receptor bind to antegion ,
        
        lymph then is activated
      - maturation
        
        b cells mature in red bone marrow
        
        during this stage lympocytes delveop immunocompetence and self tolerance
        
        lymphocyte precursors destined to become t cells migrate to thymus
      - proliferation and differentiation
        
        activated lymphoctes multiply
        
        memory cells and effector t cells circulate continulously in the blood and lymph throughout whole body and secondary lymph organs
      - origin
        
        b cells
        
        t cells
        
        originate in red bone marrow
  - - - attacks particullar foregin substances
        
        takes longer to react than innate
    - - antibodies produced by lymphocytes
      - bind temporary to target cell and invade it
      - extracellular targets
    - - has cellular targets
      - lymphocytes act against target cell
        
        directly
        
        by killing infected cells
        
        indirectly
        
        by releasing chemicals which inhance inflammatory response
        
        activating other lymphocytes or macrophages
  - - - external body membranes
        
        skin
        
        secretions
        
        mucosa
        
        secretions
        
        surfaces barriers
        
        produce protective chemicals
        
        internal defenses
        
        phagocytes
        
        white blood cells ingest & digest
        
        neutrophils
        
        macrophages
        
        natural killer cells
        
        police blood & lymph
        
        kill cancer & viruses
        
        attack
        
        inflammation
        
        fever
        
        antimicrobial proteins
    - - antimicrobial protiens
      - phagocytes
      - other cells
  - - - human immunodeficciency virus
      - destroys helper T cells
      - can enter body...
        
        sexual intercourse & oral sex
        
        blood contaminated needles
        
        mother to fetus
        
        blood transfusions
      - multiplies in lymph
      - symptoms begin when immune system collapses
        
        swollen lymph nodes
        
        night sweats
        
        severe weight loss
      - viral DNA helps enable it to reproduce
      - you get HIV before AIDS if untreated you have a higher percentage of progressing to AIDS
    - - caquired immune deficiency syndrome
      - no cure
      - virus can come resistant
      - antivirals can help
      - chronic, potentally lifethreatening caused by HIV
      - lower than 200 count t cells
      - after years of having HIV it turns into AIDS
  - - - dendritic
        
        epidermis
        
        connective
    - - attack cells that lack "self" cell surface receptors
    - - usually become helper t cells
      - some become reguatory t cells
    - - wbcs that ingest and digest
        
        neutrophil
        
        macrophage
    - - become cytotoxic t cell s
    - - play role in adaptive immune response
      - activate both arms
    - - directly attack and kill other cells
    - - secrete inhibitory cytokines
- - - - medications can slow progressions
        
        can reduce the amount of deaths caused by AIDS
      - medication doesnt always work
    - - fewer you have the weaker your system becomes
        
        AIDS is diagonosed when this t cell count falls below 200
  - - - does not go away
      - he will weaken over time
    - - HIV progresses into AIDS
      - even with some treatments HIV will turn into AIDS
- - - - the more it destorys your t cells the weaker your immune system becomes