Cirrhosis is the end stage of chronic liver disease that is progressive and irreversible. It can be caused by multiple factors, including alcohol abuse, chronic hepatitis B or C infections, prolonged biliary obstruction, or long-term severe right-sided heart failure. The disease cannot be cured but progression can be slowed with the use of diuretics to reduce fluid retention and ascites, meds to reduce nitrogen load, beta-blockers, anemia treatment, nutritional therapy, and possible surgery as the last resort.