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Autonomic NS (Classification: (1- Cholinergic Agonists (Cholinomimetics),…
Autonomic NS
Classification:
1- Cholinergic Agonists
(Cholinomimetics)
Indirect acting (Irreversible)
Ecothiophate
(Organophosphate)
Direct acting
2- Cholinergic Antagonists
3- Adrenergic Agonists
4- Adrenergic Antagonists
Drugs alter autonomic NS by either:
1- Affecting the synthesis, storage, release or reuptake of the neurotransmitters.
2- Stimulating or blocking their receptors.
Receptors:
Cholinergic
(ACH)
Nicotinic
Ganglion transmitter
Muscarinic
M1 - M5
Adrenergic
(AD,NAD)
a1
a2
B1
B2
B3