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Topic 10.1: Genes (Sickle cell anemia is an inherited form of anemia — a…
Topic 10.1: Genes
Sickle cell anemia is an inherited form of anemia — a condition in which there aren't enough healthy red blood cells to carry adequate oxygen throughout your body.
These irregularly shaped cells can get stuck in small blood vessels, which can slow or block blood flow and oxygen to parts of the body.
There is no cure for most people with sickle cell anemia. But treatments can relieve pain and help prevent problems associated with the disease
The red blood cells are flexible and round. In sickle cell anemia, the red blood cells become rigid and sticky and are shaped like sickles or crescent moons.
Mutations are random changes, no mechanism has been identified.
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Genetics: Branch of biology that studies the storage of information in living organisms and the way in which information is transmitted from parents to progeny.
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Gene: Heritable Factor, Consists of a lenght of DNA, thousands of genes conform a chromosome.
Genes are linked in groups, each group corresponds to one of the types of chromosome in a species.
Allele: A specific form of a gene; normally you inherit one allele from your mother, and one from your father.
These copies could be two of the same allele, homozygous, or two different alleles, heterozygous.
Locus: the specific position of a gene on a chromosome. To designate it, a code of numbers and letters is used, each gene has a unique identification code.
Animals and plants have two copies of each type of chromosome, so we can expect two copies of a gene to be present.
A gene consists of a length of DNA with a bases sequence that can be hundreds or thousands of bases long.