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Thioureylenes Carbimazole (Side effects (Enlarged lymph nodes, Fever,…
Thioureylenes
Side effects
Enlarged lymph nodes
Fever
Joint pains
Deppresion of white cell count
Rashes
Indications
Thyrotoxicosis
Prepare patients for thyroidectomy.
Sensitivity to Carbimazole
Graves' disease
Hyperthyroidism
Contraindications
Infection
Sensitivity to Thioureylenes
Breast feeding women
Large Goiter
Pregnant women
Mechanism of Action
Prevent oxidation of iodide to iodine
Inhibits thyroid hormone production
Propylthiouracil blocks the conversion of T3 to T4
in target tissues
Route of Administration
Oral
Storage conditions
Protect from moisture
Keep the storeroom well ventilated
Between 15 and 30 °C
Keep direct sunlight out of the storeroom
