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4d
Properties of synapse (1.convergence & divergence (Convergence…
4d
Properties of synapse
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mechanism:
- repeated stimulation
of presynaptic neuron
leads to decrease
& finally disappearance
of the postsynaptic response
cause:
due to
- exhaustion of neurotransmitters
( as its synth is not as rapid
as its release
due to
gradual inactivation
of Ca2+ channels
which decr the intracellular Ca2+
- acclimitaion of waste products
- refractiveness of the
postsynaptic membrane
to the neurotransmitter
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is the time taken required
for the passage of impulse
frm presynaptic to
postsynaptic terminal
normal- 0.5msec
- for diffusion of NT thru the
synaptic cleft to the
postsynaptic membrane
- for the action of NT on
the postsynaptic membrane/
for opening of ion channels
- for the diffusion of ions, &
changes in resting MP
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6.summation
- require subminimal stimulation
which produces EPSP
temporal
summation
- when 2 or more
presynaptic neurons
are stimulated with
subminimal stimuli
-
spatial
summation
- if(one) presynaptic neuron
is stimulated repeatedly
with subminimal stimuli
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7.Occlusion
- when 2 afferent excitatory nerves
to a skeletal muscle are
simultaneously stimulated,
it is sometimes seen that
the tension produced
by the muscle is less than
the sum of the tension
produced by each
stimulated seperately
this is because
some motor neurons
which are common to both
are excited maximally
when either is stimulated
seperately
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8 Subliminal fringe
- when 2 afferent nerves
to a skeletal muscle
are stimulated at the same time,
2 areas of depolarization
are produced.
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- the capability of
being molded/changed
depending on
past experiences
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