Thiazide Diuretics
Contra-indications
Mechanism of Action
It causes active pumping out of chloride from cells lining the ascending limb of of Henle by blocking chloride pump
Indications
Hypotension
Fluid electrolyte imbalance
Side Effects
Hyperuremia
Route of Administration
Orally
Storage
Room temperature
Hypotension
Weakness
Arrythiams
Hypokalemia
Lactaction
Pregnancy
Bipolar disorders
Gout
Systemic lupus ertythematos
Liver disease
Severe renal failure
Nursing Considerations
Acquire medical history, current medication in use
Monitor fluid intake and output the patient
Stimulating diuresis
Maintain diet that is high in potassium to compensate for excessive loss of potassium
Health education on the side effects and the medication use
Maintain electrolyte balance
Request an liver and function test
Methyclothiazide
Chlorothiazide
Mechanism of Action
Indication
Side Effects
Contradictions
Storage
Route of Administration
Edema associated with hepatic cirrhosis. congestive heart failure, corticosteriod and estrogen therapy
Hypertension
Inhibits re-absorption of Na+/Cl- in the distal tubules in the kidneys
Causing the increased loss of potassium and serum uric acid producing more urine
Producing a hypotensive effect
Room Temperature
Arrythmias
Hypokalamia
Dehydration
Electrolyte depletion
Hypochloremia
Orally
Hypotension
Pregnancy
Hypokalamia
Electrolyte imbalance
Diabetic coma
Nursing Consideration
Monitor output and intake of fluids
Monitor Electrolyte balance
Perform urine test