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Cell Cycle (Checkpoints (G1, G2, S, M (All are checkpoints, G1 regulates…
Cell Cycle
Checkpoints
G1, G2, S, M
All are checkpoints
G1 regulates growth and preps for chromosome duplication
Make sure everything is good in cycle
Go to G0 phases if not
S DNA replicates
Same as G1
Mitosis make sure duplicated cells are good
Mitosis
2 identical cells
Cell division
Two daughter cells
Sister chromatids are seperated
Meiosis
Sex cells division
Crossing over
4 daughter cells. Haploid and unidentica;
Homologous chromosomes and sister chromatids are seperated
Apoptosis
Cell death
Apoptosis
P53 tells when cell death should occur
Can activate DNA repair
Stem cells
Cells that differentiate
Controversial on use
Can grow into many things
Interphase
Most of the cells time is spent in here.
G1, (G0) S, G2, M
Cyclins and CDK
Advance cells into next phases
CDK levels constant, Cyclin fluctuate
Hayflick Limit
Cells can only divide 40-60 times
Telomeres shorten too much