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Mutagens (Chemical Mutagens (Ingested chemicals (Alcohol, 'tarin' …
Mutagens
Chemical Mutagens
Ingested chemicals
Alcohol
'tarin' - tobacco smoke
some medications
Environmental irritants
Organic solvents
cleaning products
Asbestos
Intercalating Agents
Chemicals that disturb bonds between bases
Error in DNA replication
DNA reactive chemicals
chemicals that replace bases
DNA does not have correct base sequence and cannot function.
Base Analogues
chemicals that react with DNA
forms cross-links or breaks DNA strand
Naturally occurring mutagens
Biological mutagens
Microbes
are naturally occurring biological mutagens
Bacteria
Helicobacter
Fungi
Viruses
Epstein-Barr
Hepatitis B
Transposons
short DNA sequences that spontaneously fragment and relocate or multiply within the genome.
Cause errors in replication and chromosome duplication.
Cause errors in replication and chromosome duplication.
Non biological
Naturally occurring mutagens
Metals
mercury
cadmium
Physical Mutagens
Heat and ionising radiation
Electromognetic radiation (heat)
comes from the sun
Seven areas in the spectrum
radiowaves
microwaves
infrared
visible light
Ultraviolet
X-Rays
gamma rays
Ionising radiation
The shorter wavelength and high energy dangerous
it can split off electrons causing damage in cells.