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Chapter 16: Genetics (Monohybrid Crosses (Crossing Heterozygote with Self:…
Chapter 16: Genetics
Monohybrid Crosses
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3:1 Ratio: offspring of heterozygous parents, 75% dominant 25% recessive
Mutations
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deletion: piece of DNA lost
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Effects:
effects & significance depends on nature, position, & extent
changes to introns: unimportant generally, will not be incorporated into final mRNA
changes to exons: unimportant if changed codon is similar to previous, or located in noncritical location
the larger the mutation, the higher chance that a critical part of DNA is affected
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Dihybrid Crosses
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Independent Assortment:
if the 2 genes are on separate chromosomes, the alleles of one move independently of the other
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Linkage:
when two genes occur close together on a chromosome, considered linked
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Replication of DNA
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chromatin becomes less compact, opening to allow replicating factors
one strand of double helix cut, two strands separate
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replication fork: as DNA uncoils & separates it takes on forked appearance