70 year old woman goes to emergency room with difficulty breathing and discovers she has developed a viral infection of the lungs

Fast, shallow breathing and wet, wheezy cough

As an older person, her body is unable to adjust to the higher altitude like a young person can

She is at a much higher altitude in Denver than she is in Fort Worth

Body tries to use acclimatization, an adaptive response to make respiratory and hemotopoietic adjustments

Age effects

Fast shallow breathing effects

Cerebral blood vessels constrict when carbon dioxide decreases below what it should be in your system

More vulnerable to infections since your immune system is weaker

Elasticity of alveoli decreases, they lose their shape and become baggy

Rib cage can't expand and contract while breathing because the bones are more thin and have changed shape

Pneumonia could result if she doesn't get treatment

Location with higher altitude effects

Lower air pressure at high altitudes makes it more difficult for oxygen to enter our system

Lymphatic system interaction

Lymphatic system protects respiratory organs from bacteria, bacterial toxins, viruses, protozoa, fungi, and cancer

Circulatory system interaction

Blood transports respiratory gases

The two systems work together to circulate blood and oxygen throughout the body

Lung anatomy

Type I cells

Type II cells

Simple squamous epithelium

Make up major part of alveolar wall

Stratified cuboidal epithelium

Secretes antimicrobial proteins important for innate immunity

Secretes surfactant that coats the cells

Surfactant reduces surface tension and prevents the collapsing of lungs

Macrophages

Move along alveolar surface

Eat dust, bacteria, and other debris

Alveolar duct (how they get there)

Alveolar sac (group, alveoli)

Alveolus (one single)

Branches of the bronchi

Primary, secondary, tertiary

Cardiac notch

Space for heart

Inflammation of the respiratory system effects

Asthma

Wheezing

Inflamed alveoli make it difficult for oxygen to pass through

Alveolar level respiratory physiology

Carbon dioxide pressure in alveoli must be lower than the blood

Oxygen pressure must be higher in alveoli than the blood

Carbon dioxide diffuses from bloodstream into alveoli

Oxygen diffuses from alveoli into bloodstream

Travels from alveolar ducts to the alveolar sacs, then into the individual alveolus

Gas laws

Boyle's law

If volume increases, pressure decreases (inverse relationship)

Dalton's law

Nitrogen, oxygen, and carbon dioxide all act indepently

Henry's law

Solubility of nitrogen, oxygen, and carbon dioxide are all different (when in contact with surface of a liquid)

Partial pressure and how elevation affects it

Partial pressure is directly proportionate to the percentage of that gas in the mixture

Partial pressure is the pressure exerted by each gas

Elevation affects partial pressure because the amount of nitrogen, oxygen, and carbon dioxide in higher or lower altitudes is different to sea level

Low altitudes- for every 33 feet of descent below sea level, atmospheric pressure increases by 1 atm

High altitudes- partial pressure declines in direct proportion to the decrease of atmospheric pressure