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Tumor Immunology (Tumor Evasion of immune response (Factors related to…

- - - - Examples of successful monoclonal ab
        
        Anti-CD20 (Naked/radioactive iodine for B-cell Lympomas
        
        Herceptin(Breatstcancer with high levels of her2)
- - - - Direct cytotoxicity
      - Cytokine secretion
      - Antigen presentation
      - Killing of tumor cells by adcc
  - - - ADCC
      - Complement attachment for Mac
    - - Tc cells
      - Th cells
        
        IFN-y which activates macrophages, and NK
        
        TNF which is directly toxic to tumors
        
        IL-2 that activates Tc, NK, and B-cells