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Bacterial Infections (Tuberculosis (Types of tuberculous Disease (TB…
Bacterial Infections
Tuberculosis
Definition
chronic infection caused by mycobacterium tuberculosis
Mode of infection
epidemiology
Pathogenesis
Alveolar macrophage
bactremia and seeding
replication in macrophage
antigen presentation
T-cell response
Lymphokine activate macrohpage
Granuloma formation
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Tissue reaction
Tubercle( Proliferative)
Morphology
Microscopic
Gross
Tubercle fate
High Immunity
Small Leisons
Large lesions
Low immunity
Spread(4)
Direct spread
lymphatic spread
blood spread
intracanalicular spread
Exudative tissue reaction
Definition(occurrence of the reaction)
Reaction charcteristics
Types of tuberculous Disease
General types
secondary
extrapulmonary
Primary
pulmonary TB
Primary
Pathological features
Fate of primary complex
Healing
Spread
Blood
Moderate Number
Isolated organ tuberculosis
Large number
Millary TB
Small Number
Direct
Bronchial
Encapsulation and reactivation
Clinical picture
Secondary
Cause
Course
Chronic fibro-caseous pulmonary tb
Charcteristics
Gross
Microscopic
Complications
Clinical picture
Tuberculous Bronchopnemonia
Pathological features
Description
Regression
Common Targets
Lesion Beginning
Millary Tuberculosis
Intestinal
Primary
Description(Pathologic features)
Lymphangitis
Lymphadenitis
Intestinal lesion
Fate
Secondary
Complications
Gross
Tonsilar TB
Primary( descripe)
Common in
Cause
Primary tonsillar complex
Secondary
Cause
Lesion(Caseous, ulcer, cold abcess)
TB lymphaddenopathy
Gross
Late
Early
Microscopic
Descripe
Complications
TB of skin
Lupus vulgaris
Primary tb
Occurence
Complex
Infectious Disease
Definition
Types of infection
Putrefaction
Toxic infection
Endotoxin
Exotoxin
Pyogenic
localized(abscess)
Diffuse (acute suppurative appendicitis)
Opportunistic
Course and fate of any infection
Inflammatory reaction
Chronic(Fibrous tissue prevents spread
Immune response attacks organism and prepares for healing
Gamma interferon protects against viruses
Phagocytic activity to clear debris for healing
Acute(fibrinogen prevents spread)
Failure
Direct spread
Distant spread
Lymphangitis
Lymphadenitis
Generalized lymphadenitis
blood stream
Toxemia
septicemia
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Bacteriemia
Pyaemia
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Factors affecting infection
factor related to Host resistance
Natural mechanisms
Induce immune mechanisms
Factors related to organisim
Dose
Virulence
Adhesive properties
Toxin production
Ability to evade phagocytosis and enzmye attack
Syphilis
Lesions or stages
secondary
Sites
Gross
onset
Micro
Clinical Picture
Tertiary
Onset
forms
Diffuse syphilitic inflammation
Definition
Fate
Sites
Gumma
gross
MS
Fate
Definition
Examples
Sites
Primary(Hard chancre)
sites
Gross
Onset
MS
Tissue reaction
Mode of infection
Direct
Congenital
Definition
Actinomycosis
Pathological features
Gross
MS
Types
Definition
Leprosy
Etiology and parthenogenesis
Source
site
Organism
Types
Tuberculoid
Definition
Lesions
Nodular
Definition
Lesions
Definition
