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Homeostasis (Hormones (Insulin (Promotes (Use of glucose as the primary…
Homeostasis
Hormones
Insulin
Pancreatic hormone that facilitates entry of glucose and amino acids into the cell, conversion of glucose into glycogen and transport of fats into adipose tissue
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Promotes
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Storage of glycogen in the liver and muscle, fat in adipose tissue and proteins in muscles
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Angiotensin
Peptide hormone that constricts blood vessels, causes retention of sodium and water and produces thirst and salt apetite
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ANP
Hormone secreted by heart. Reduces blood pressure, inhibits drinking and promotes the excretion of water and salt at kidneys.
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Angiotensin II
Substance produced in the blood by the action of renin and that plays a role in the control of thirst
Leptin
High leptin levels activate appetite, suppressing POMC neurons and inhibit appetite, increasing NPY neurons.
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Thirst
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Extracellular fluid
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Interstitial fluid
Fluid bathing the cells, filling the space between the cells of the body. Isotonic.
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Osmometric thirst
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Increase draws water out of the cells and as a result, they shrink in volume
Sweating and urinating makes us lose more water than salt which increases the concentration of extracellular fluid
Produces activation in the anterior cingulate cortex, the hypothalamus and the lamina terminalis.
Osmoreceptors
Neuron that detects changes in the solute concentration of the interstitial fluid that surrounds it.
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As concentration changes, they either shrink or expand.
Fluid regulation
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Brain releases vasopressin which induces additional constriction of blood vessels. It instructs the kidney to reduce flow of water to bladder
Kidney's release renin into the circulation, which triggers a hormonal cascade that brings angiotensin II which has water conserving actions.
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Digestion
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Ejection
Remaining water and electrolytes are absorbed in the large intestine and the rest are ejected from the anus
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Theories
Set-point assumption
View that hunger implies energy deficit and that by eating, energy resources of the body are returned to the optimal level.
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Lipostatic theory
Every person has a set point for body fat and deviations produce compensatory adjustments in the level of eating, returning body fat to set point
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Hunger
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Lateral hypothalamus
Chronic satiety, aphagia and severe weight loss
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Metabolism
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Three phases
Cephalic phase
Preparatory phase
Digestive phase: Food entering stomach causes release of gut hormones and stimulates pancreas to release insulin
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Fasting phase
Period where all un-stored energy from previous meal has been used and body is withdrawing energy from it's reserves to meet immediate energy requirements
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Factors
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How much we eat
Satiety signals
Food in gut and glucose entering blood induce satiety signals, inhibiting consumption
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Serving size
The larger the serving, the more we eat
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