Adverse reactions: drowsiness, sedation, seizures, dizziness, syncope, vertigo, headache, tremor, disturbed sleep or nightmares, restlessness, hypokinesia or akinesia, agitation, rigidity, akathisia, confusion, fatigue, insomnia, hyperkinesia, weakness, lethargy, ataxia, slurred speech, depression, myoclonus, anxiety, neuroleptic malignant syndrome, fever. leukopenia, agranulocytosis, eosinophilia, neutropenia, thrombocytopenia.
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Warn patient about risk of developing agranulocytosis. Safe use of drug requires blood tests weekly during treatment.
Advise patient to promptly report flulike symptoms, fever, sore throat, or other signs of infection. Also, tell him to report unexplained fatigue, difficulty breathing, irregular heart rate, or leg or ankle swelling.
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