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Alzheimer Disease (systemic alteration (impaired swallowing (leads to…
Alzheimer Disease
systemic alteration
impaired swallowing
leads to undernutrition which causes weight loss, muscle weakness and eventually metabolic acidosis without nutrients
incontinence
increasing episodes can lead to massive losses in fluids and electrolytes which can lead to hypovolemic shock
loss of memory
may cause patient to become disoriented and withdrawn which can lead to mental illnesses like depression and anxiety
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decreased movement
leads to sarcopenia from the lack of activity which leads to loss of skeletal muscle and accumulation of fat
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diagnoses
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mental examination( determines time and place, communication ability, memory, and comprehension)
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treatment
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cholinesterase inhibitors(compensate for the depletion of ACH in the cerebral cortex and hippocampus)
Neurodegeneration
caused from
Senile plaques
plaques are comprised of
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contains beta-amyloid(Ab), a protein fragment of amyloid precursor protein(APP)
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Neurofibrillary tangles
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accumulate at the temporal lobe and eventually becomes concentrated in the medial temporal lobe and the hippocampus
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tangles continue to form and impinge on motor, executive, and sensory function
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