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Diuretic Drugs (Carbonic Anhydrase Inhibitors (Indications (treatment of…
Diuretic Drugs
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Overview
Eight report of Joint national committee ob prevention, detection, evaluation, and treatment of high blood pressure reaffirmed the role of diuretics as one of the first line drugs in the treatment of hypertension
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causes direct arteriolar dilation, which decreases peripheral vascular resistance
reduces extracellular fluid volume, plasma volume, cardiac output, which may account for the decrease in blood pressure
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Loop Diuretics
Bumetadine, Furosemide, and toresemide are chemically related to sulfonamides
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indications- used to manage the edema associated with heart failure and hepatic or renal disease, to control hypertensions, and increase renal excretion of calcium pt with hyperkalemia
contraindications- hepatic coma, and severe electrolyte loss; allergy to sulfonamide
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