CRETINISM

INTRODUCTION

is a condition characterized by physical deformity and learning difficulties that is caused by congenital thyroid deficiency

CAUSES

a genetic defect that affects thyroid hormone production

too little iodine in the mother diet during pregnancy

Caused by a missing, poorly formed, or abnormally small thyroid gland

use of medication that disrupt thyroid hormones production during pregnancy

PATHOPHYSIOLOGY

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Thyroid gland develops from the buccopharyngeal cavity between 4 to 10 week gestation

The thyroid arises from the fourth branchial pouches and uitimately ends up as abilobed organ in the neck

Erros n migration of thyroid tissues can resuit in thyroid aplasia

By 10-11 week's gestation, thefetal thyroid is capable of producing thyroid hormone

SYMPTOMS

Stunted growth

Fatigue, lethargy

Lack of weight gain

Poor feeding

Thyroid hormones to control conditon

Intravenous fluids

Take iron supplement

Gives levothyroxine within first four weeks after birth