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Renal Cell Carcinoma (Clinical Presentation (Polycythaemia in 5%,…
Renal Cell Carcinoma
Clinical Presentation
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Rarely, invasion of the LEFT RENAL VEIN results in the compression of the left testicular vein resulting in a VARICOCELE
Anorexia, malaise and weight loss
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Haematuria, loin/flank pain and abdominal mass
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Diagnosis
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Bloods - FBC (polycthaemia & anaemia due to EPO decrease), ESR may be raised, liver biochem may be abnormal
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Pathophysiology
Spread may be direct (renal vein), via lymph or haematogenous (bone, liver, lung)
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Treatment
Ablative techniques
Such as cry oblation and radiotherapy are used in patients with significant comorbidities who would not tolerate surgery
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Differential Diagnosis
Transitional cell carcinoma, Wilms' tumour, renal oncocytoma, leiomyosarcoma