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The Host Response, Chronic Inflammation: Long-term and out-of-control…
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The complement system is series of proteins in the blood, working to facilitate phagocytosis or kill bacteria by puncturing the cell membranes
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PMN's
First responder, 2-4 days
Release lysosomes and cytokines and starts walling off pathogens. Also releases chemicals by chemotaxis to recruit cytokines PGE2, TNF, MMP's
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Acute Inflammation
Tissue builds clot
PMN's arrive and kill invading microorganisms. Then release toxins and cytokines while inducing the liver to create plasma proteins
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