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Cor Pulmonale :<3: (Differential Diagnosis (Primary pulmonary…
Cor Pulmonale :<3:
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Pathophysiology
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vasoconstriction caused by hypoxia, hypercapnia, or both
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Pulmonary hypertension increases after load on RV, resulting in a cascade of events that is similar to what occurs in LV failure, including elevated end-diastolic and central venous pressure and ventricular hypertrophy and dilation. Demands on the RV may be intensified by increased blood viscosity due to hypoxia-induced polycythemia
Diagnostic Test
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Echocardiography: to evaluate LV and RV function: they can assess RV systolic pressure but often technically limited by the lung disorder
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Etiology
Chronic cor pulmonale is usually caused by COPD, but there are several less common causes.
In patients with COPD, an acute exacerbation or pulmonary infection may trigger RV overload
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In chronic cor pulmonale, risk of venous thromboembolism is increased.
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