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METFORMIN (Biguanides) (side effects (cardiotoxicity, transient bone…
METFORMIN (Biguanides)
Indications
increases glucose uptake and use by target tissues, thereby decreasing insulin resistance.
contraindications
it contraindicate diabetic patients with renal or hepatic disease and those with diabetic ketoacidosis.
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mechanism of action
reduces hepatic glucose output, largely by inhibiting hepatic gluconeogenesis.
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