Pioglitazone
Definition
Is an oral antidiabetic agent that act primarily by decreasing insulin resistance. It is a drug that is found under the group thiazolidinedions. It trade name is called Actos.
Side effects
Muscle pain
Weight gain
Sore throat
Tooth problems
Contraindications
Vision problems
Bone fracture
Reddish coloured urine
Heart disease
Liver disease
Anaemia
Macular edema
Bladder cancer
Route
Actos is taken orally once daily and maybe taken without regards to meals.
Indications
Actos is indicated as an adjunct to diet and exercise to improve glycolic control in patients with type2 diabetes
Actos is indicated for monotherapy
Actos is also indicated for use in combination to use with a sulfonylurea, metformin, or insulin when diet and exercise plus the single agent does not result in adequate glycaemic control.
Storage
Store below 25 °c at room temperature