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a-glucosidase inhibitors(acarbose) (side effects (colonic ulceration,…
a-glucosidase inhibitors(acarbose)
side effects
colonic ulceration
partial intestinal obstruction
inflammatory bowel disease
patients predisposed to intestinal obstruction
cirrhosis
patients with chronic intestinal diseases
mechanism of action
reduce intestinal glucose absorption
contra-indications
in patients with known hypersensitivity to the drug
in patients with diabetic ketoacidosis
indications
used in combination with insulin or other diabetes medictions administered orally
used in management of type two diabetes
it is used with diets to treat type2 diabetes
storage
container must be kept closed very tight
store below 25 degrees, proctect from mosture
route of administration
50 mg and 100 mg tablets for oral use. precose is unavailabe at 25 mg