Alpha-glucosidase inhibitors

Mechanism of action

Dosage

Adverse effects

Contraindications

Able to slow down digestion of complex carbohydrates in the intestine, which is another route to decreasing the postprandial glucose excursion.

Abdominal pain

Diarrhea

Flatulence

Mild itching or skin rash

Strengths: 25 mg, 50 mg, and 100 mg

25 mg taken three times per day for adults

Patients with hypersensitivity to the drug

Patients with diabetic cirrhosis

Patients with congested heart failure with liver failure

Colon ulceration

Weight gain

Drugs in this class

Miglitol

Voglibose

Acarbose download

Indications

Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

eEfect on the kidneys

AGIs-induced liver injuries