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GSL2 INHIBITORS eg EMPAGLIFLOZIN (SIDE EFFECTS (PROBLEMS WITH URINATION…
GSL2 INHIBITORS eg EMPAGLIFLOZIN
MECHANISM OF ACTION
AND FACILLIATATE ITS EXCRETION IN URINE
AS GLUCOSE IS EXCRETED, ITS PLASMA LEVELS FALL LEADING TO
BY INHIBITING SGLT2 IN THE PC, TO PREVENT REABSORBTION OF GLUCOSE
AN IMPROVEMENT IN ALL GLYCEMIC PARAMETERS
GLUCOSE COTRANSPORTER 2 INHIBITS WORK
CONTRAINDICATIONS
HISTORY OF STROKE
UNCONTRO HYPERTENSION
ISCHEMIC HEART DISEASE
INDICATION
METFORMIN IS NOT APPROPRIATE DUE TO PATIENT INTOLERENCE
TYPE 2 DIABETES
WHEN DIET AND EXERCISE DOES NOT PROVIDE ADEQUATE GLYCEMIC CONTROL
SIDE EFFECTS
LIKELY URINARY TRACT INFECTIONS
GENITAL INFECTIONS WITH PAIN,ITCHYNESS AND RASH
PROBLEMS WITH URINATION
CONSISTENT URGE, LITTLE OR NO URINATION
HYPOGLYCEMIA
FEELING LIGHT HEADED AND TIRED
INCREASED CHOLESTEROL
DOSAGE
10mg to 25mg