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intermediate acting insulin eg. NHP insulin (side effects o NHP insulin…
intermediate acting insulin eg. NHP insulin
duration
onset is about 1 to 2 hours
peak time is 4 to 12 hours
exact duration is 18 to 24 hours
role
covers insulin needs for about half a day or overnight
it is combined with rapid or short acting type.
indication
given to help control blood sugar levels in people with diabetes. I
route of administration
It is used by injection under the skin once to twice a day
side effects o NHP insulin
pain
skin changes at the site of in jection
low blood potassium
allergic reactions
mechanism of action
acts on specific receptors located on the cell membrane of practically every cell,
their density depends on the cell type: liver and fat cells are very rich.
stimulates glucose transport across cell membrane by ATP dependent translocation of glucose transporter GLUT4 to the plasma membrane.