Please enable JavaScript.

Coggle requires JavaScript to display documents.

Pain (Harm reduction with opioids (Lowest effective dose, Shortest…

- - - - Influenced by comorbidities
- - - - Transduction
        
        Conduction
        
        Transmission
        
        Modulation
        
        Perception
      - Nociceptive process in response to noxious stimuli (temp, chemical, mechanical)
    - - Caused by damage or abnormal functioning of PNS/CNS; neuropathic pain
        
        PNS: nerve fiber sensitivity, altering Na channels
        
        Increased pain
        
        CNS: hypersensitivity of central neurons, central sensitization
      - Neuropathic pain, fibromyalgia, IBS