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Reactive Arthritis (Clinical Presentation (Circinate balanitis - painless…
Reactive Arthritis
Clinical Presentation
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Arthritis is typically an acute, ASYMMETRICAL, lower-limb arthritis
Treatment
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Majority of individuals with reactive arthritis have a single attack and it settles, but a few develop disabling relapsing and remitting arthritis
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If that doesn't work, use TNF-alpha blockers but rarely necessary
Diagnosis
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Aspirated synovial fluid is sterile with high neutrophil count - if the joint is hot and swollen can exclude crystal arthritis
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Key Facts
Sterile inflammation of the synovial membrane, tendons and fascia triggered by an infection at a distant site, usually GI or genital
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Pathophysiology
Bacterial antigens or bacterial DNA have been found in the inflamed synovial of affected joints - suggesting that his persistent antigenic material is driving the inflammatory response