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DIGESTION AND METABOLISM OF LIPID (Dietary fat Composition (Triglycerides…

- - - - • Acidic , Preferentially hydrolyse tryglyceride with shortand medium-chain fatty acids (< 12 C atoms)
      - • Form 1,2-diacylglycerol
      - • The free fatty acid can readily cross the epithelial membrane lining the GIT but the diacylglycerol cannot be transported across.
  - - - • two primary bile acids, cholic acid and chenodeoxycholic acid
      - • formed in the liver from cholesterol, and secreted/stored into the gallbladder.
      - • The bile acids are amphipathic,hydrophobic sides towards the fat and hydrophilic towards the outside.
- - - - circulation
- - - - forming fatty acyl-carnitine
        
        shuttled across the inner mitochondrion membrane by carnitine acylcarnitine translocase to the matrix
  - - - CITRIC ACID CYCLE
        
        ELECTRON TRANSPORT CHAIN
- - - - Mixed micelle
        
        Enterocytes (Intestinal mucosal cells)
        
        Bile salts reabsorbed further down into GIT (ileum).
        
        Recycled and secreted back into digestive system.