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Thiazolidinediones (Side effects (Cardiac failure, Osteoporosis, Edema,…
Thiazolidinediones
Side effects
Cardiac failure
Osteoporosis
Edema
Weigh gain
Dosage
15mg
30mg
45mg
Mechanism of action
Reduced insulin resistance through the stimulation of PPARs
Increased transcription ofadipokines
Contraindications
Liver failure
Congestive heart failure
Group name
roliglitazone
pioglitazone
Indication
supplement to sulfonylurea
type 2 diabetes mellitus