Please enable JavaScript.
Coggle requires JavaScript to display documents.
DIGESTION AND METABOLISM OF CARBOHYDRATE (DISACCHARIDE (Types (Sucrase-…
DIGESTION AND METABOLISM OF CARBOHYDRATE
FINAL HYDROLISIS - LUMINAL SURFACE OF SMALL INTESTINE EPITHELIAL CELLS
Exoenxymes
Cleave one unit glu at a time
Alpha-glucosidase
Beta- glucosidase
DISACCHARIDE
Types
Sucrase- isomaltase
(bifunctional enzyme catalyzing hydrolysis of sucrose and isomaltose)
Lactase
Maltase
Present in the bush border epithelium of intestinal mucosal cells
Reactions catalyzed
Sucrose Isomaltose :arrow_right: 3 Glucose + Fructose
Lactose :arrow_right: Glucose + Galactose
Maltose :arrow_right: Glucose + Glucose
IN STOMACH
Action
No enzyme for glucosidic bond cleavage
Hydrochloride (HCl) can hydrolyse sucrose from fructose and glucose
IN MOUTH
Action of Ptylin (Salivary amylase)
Incomplete process
Location: mouth
Shorter duration
Action
Require Cl- ion for activation of optimum pH of 6.7 (Range 6.6 to 6.8)
Alpha- amylase hydrolyse alpha-1,4 glycosidic linkage in polysaccharide molecule
Type of amylase : Alpha- amylase
Ptylin action stops in stomach (pH falls to 3.0)
IN SMALL INTESTINE
Main digestion take place in small intestine by pancreatic amylase
Digestion completed by pancreatic amylase (food stay longer time in intestine)
in duodenum
food bolus meets pancreatic juice
pancreatic juice contain pancreatic amylase @ amylopsin (carbohydrate splitting enzyme - similar to salivary amylase)
food bolus reach duodenum from stomach
Action of pancreatic amylase
Reaction catalyzed
Starch :arrow_right:Maltose/isomaltose + Dextrins and oligosaccharides
Pancreatic amylase product
trisaccharide maltotriose
alpha-limit dextrin (~ glucose unit with 1 or more 1,6 glucosidic bond)
Disaccharide maltose
An isoenzyme of salivary amylase but differ in optimum pH of action
Require Cl- ion for its activity
Optimum pH: 7.1
Hydrolyse alpha-1,4 glycosidic linkage of polysaccharide molecule
Type of amylase: Alpha-amylase
OTHER UNHYDROLYSED CANNOT BE ABSORBED
Enter lower tract of intestine
Used by bacteria resulting in producing of
Methane
CO2
Hydrogen gas