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THE PANCREAS pancreas (Characteristics of Pancreatic Juice (Colourless,…
THE PANCREAS
Function
Endocrine
Islet of Langerhans: Secretes insulin or glucagon
Exocrine
Acini: Secretes pancreatic juice
Characteristics of Pancreatic Juice
Colourless
ph 7.1 - 8.2
Consists of water, bicarbonate, salts & pancreatic enzymes
Produced 1.5 L/day
Regulation of Pancreatic Secretion
-Secretin stimulates pancreatic juice
-Acidic chyme enters small intestines
-During cephalic phase and gastric phase of gastric secretion, impulse from vagus nerve(x) also stimulate chyme
-CCK stimulates pancreatic enzymes
Action of pancreatic enzymes
complete digestion of food requires
pancreatic enzymes or juice secretion
stimulated by
Secretin + CCK
Zymogens (inactive pancreatic enzymes)
brush border enzyme
act on
Trypsin (active)
triggers the activation of
Trypsinogen (inactive) secreted by acinar
into
