Cardiovascular system

Blood

Blood delivers nutrients and oxygen to vertebrates.

Red Blood Cells

White Blood Cells

Platelets

Delivers oxygen to organs and tissues

Fights infections

Stick together to form clots

Plasma

55% water

Contains: Protein, Glucose, Mineral ions, hormones, & carbon

Blood Cell Disorders

Thalassemia

Anaemia

Sickle Cell

Haemophilia

Leukemia

Blood Cancer (Malignant white blood cells multiply inside bone marrow) & involves production of abnormal WBC'S

RESULT: Difficult for body to fight off infection, control bleeding & transport oxygen

Chromosome Translocation: A portion of 1 chromosome breaks off & attaches to different chromosome.

Red blood cells become the shape of a sickle and break down

leaves a shortage of RBC'S

Group of inherited blood disorders

CAUSED BY: genetic mutations the present normal production of hemoglobin(carried oxygen)

NEED: Blood transfusion and to maintain healthy RBC'S

RESULTS: Enlarged spleen, bone deformity and heart problems

Lack of blood

RESULTS: Fatigue, skin pallor, shortness of breath, lightheadedness, dizziness, or a fast heartbeat.

Blood doesn't clot normally

Excessive bleeding

RESULTS: many large or deep bruises, joint pain and swelling, unexplained bleeding, and blood in urine or stool.

Blood groups

B

A

AB

O

AB+ Universal Plasma donor

O- Can be given to anyone yet, still might have bad results

Myths of blood donation:

Can't donate because low iron

Can't donate because diabetic

Can't donate because High Blood Pressure

Can't donate because I take medication

Can't donate because high cholesterol

Can't donate because tattoo

As long as blood pressure is below 180 systolic and 100 diastolic

Iron rich foods help blood production

It must've been done by a licensed artist

sit must be clean, dry and pain free

has to be 24hrs after last dose of antibiotics and symptom free

Closed system to heart & blood vessels

Heart pumps blood

Blood vessels circulate blood to all parts of body

Function:

Location:

Covering:

Wall:

Delivers oxygen and nutrients

Takes out Carbon Dioxide & waste

Base of right shoulder & sits at 2nd rib

Pericardium

Visceral pericardium(epicardium)

Parietal Pericardium

Pericardial cavity

Double Serous Membrane (Produces serous fluid)

Closest to heart

Outer layer (sac)

Space between visceral & parietal

Contains serous fluid ( reduces friction when heart is pumping)

Epicardium

Myocardium

Endocardium

Inner layer

Outer layer

Middle layer (muscle layer)

Types of Circulation

Pulmonary circulation

Systemic Circulation

Coronary Circulation

Blood flows to myocardium

Coronary Arteries: Supplies blood to heart

Cardiac Veins: Carries blood away from heart

heart to lungs with Pulmonary Arteries

Lungs to heart with Pulmonary veins

WHOLE blood flow

Heart Valves

Atrioventricular Valves(AV)

Semilunar Valves

Tricuspid Valve

Bicuspid Valve

Pulmonary Valve

Aortic Valve

3 flaps

2 Flaps

Prevents blood from right ventricle from re-entering right atrium

Prevents blood from leaving left ventricle & going back into left Atrium

Between right ventricle & pulmonary trunk

Prevent blood from re-entering right ventricle from pulmonary trunk

Between left ventricle & Aorta

Prevents blood from Aorta back into left ventricle

Cardiac Cycle(1 Complete Heart Beat)

Mid-to-late Diastole(relaxed)
-Both ventricles & atria are in middle or late phase of relaxation
-Ventricles are being filled with blood

Early Diastole
-Beginning phase of relaxation
-Atria finish filling and Ventricle pressure is low

Ventricular Systole(Contraction)
-When ventricles are filled with blood & pressure builds up
-Ventricles contract; pushing blood out to Aorta or Pulmonary Arteries

Heart Sounds

Lub: Caused by opening and closing of Av Valves (LONG)

Dub: Caused by opening and closing of Semilunar Valves (SHORT)

Elements of Intrinsic Conduction

System: **SA Node -->> AV Node -->> AV Bundle -->> Bundle Branches -->> Purkinje Fibers -->> Ventricular Wall**

Sinoatrial(S-A) Node : "Pacemaker"
-LOCATED: Right Atrium ; Starts heart beat & sets pace
-Sequential Stimulation occurs at other Autorhythmic cells

Atrioventricular (A-V) Node : at junction between Atria & ventricles

Atrioventicular (AV) Bundle (bundle of his)
-Right and left bundle branches

  • LOCATED: at the interventricular septum

Purkinje Fibers
-Specialized myocardial muscle fibers
-Conduct electrical impulse; spread within muscles of ventricular wall

Vascular System

Capillaries

Veins

Arteries

Venules

Arterioles

-Branched from Arteries
-Farther from heart
-Small, then become smaller to capillaries

-Major blood vessels
-Carry blood away from heart

-Smallest blood vessels
-Sites of gas exchange between blood & tissue cells

-Returns blood back to heart

-"Small veins"
-Connects capillaries & veins

Blood Vessel Anatomy

Tunica(layer) Intima

Tunica Media

Tunica Externa

Endothelium (inner lining of Blood Vessels)

Middle, Smooth muscle layer; controls (Sympathetic NS) diameter of Blood Vessels

Outermost, Fibrous connective tissue

Cardiovascular Disorders

Pericarditis

Angina Pectoris

Myocardial Infraction

Murmur

Valve Stenosis

Fibrillation

Varicose veins

Crushing chest pain from lack of blood in myocardium

Indication of a myocardial infraction(heart attack)

pain may be due to sore chest muscles

Inflammation of pericardium

Commonly Caused By: viral infections which cause fluid build up in the pericardial cavity & stops heart from expanding & contracting to pump blood

Heart muscle cells die due to lack of blood

Caused by: Atherosclerosis(Narrowing of the coronary arteries)

Symptoms: Angina Pectoris(chest pain), pain down left arm, shortness of breath, fever, & vomiting

Abnormal/irregular heart sounds

Caused By: Valve Stenosis

Defect in valves failing to open which makes heart pump harder

Can happen to ANY valve
-worst case is the mitral valve stenosis

Rapid uncoordinated shuddering of myocardium; preventing heart from acting as a pump

Caused By: defect in intrinsic conduction system, specifically the SA node(pacemaker)

swollen, twisted, typically in legs, skeletal muscles pushing on vein forcing it towards surface

Caused By: when valves in veins dont work & cause flow or pooling of blood