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Osteomyelitis (Treatment (Home antibiotic infusion (Stable tx, Motivated,…

- - - - Vanc IV plus ceftriaxone IV
    - - Add metronidazole or clindamycin IV OR substitute ertapenem for ceftriazone
  - - - 8w if MRSA in adults
        
        3-4w if septic arthritis
- - - - Multiple bones
    - - Polymicrobial
      - S.aureus, E.coli, strep
    - - Result of pressure ulcers & DM foot infection
  - - - Diabetic foot infections
  - - - Tenderness, warmth, edema, erythema
    - - Fever, elevated WBC
- - - - Generally one bone (long-bones)
    - - Monomicrobial
      - S.aureus (80%); E.coli & strep (20%)
      - 3mo-4yr K.kingae
    - - Bacteria deposits
        
        Neonates: spreads to joints
        
        12-18 mo: abscess
        
        Adults: intramedullary
  - - - Fever, chills, malaise
    - - Pain, swelling
- - - - Not indicative of severity, but good for monitoring
    - - For everyone besides chronic osteomyelitis