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NATEGLINIDE (ADVERSE EFFECT (Lactic acidosis, Abdominal pain, Nausea,…
NATEGLINIDE
ADVERSE EFFECT
Lactic acidosis
Abdominal pain
Nausea
Shock
Anorexia
Drowsiness
MECHANISM OF ACTION
Stimulate insulin released from the pancrease
Works by restoring early phase insulin realise
Reduces mealtime glucose excursion
Quickly absorbed from the GI tract
Synthesises with metformin
INDICATIONS
Helps the body to respond well to insulin
It is used together with diet in old patients to control blood sugar
Control blood sugar level
CONTRA INDICATION
Type 1 diabetes
Diabetic ketoacidosis
Known hypersensitivity to the drug :
EFFECT ON THE KIDNEYS
Causes impaired renal function
DOSE
120mg immediately before breakfast
STORAGE
Store at 20 to 25 degree celcius