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Pioglitazone 40115_S_Actos_Box-L (contraindications (, breastfeeding women…
Pioglitazone
Side effects
oedema
perpetrates congestive heart failure
fluid retention
Mode of Action
leads to increased protein transcription
results in improved insulin sensitivity
Agonist of nuclear receptors
Dose
increase to 30 mg after one to three months if necessary.
do not exceed 30 mg in the primary care setting
Start with 15 once daily in the morning
Maximum registered dose is 45 mg daily.
contraindications
, breastfeeding women
, liver disease
Pregnant women
CCF
not use same time with insulin (Greenstein, 198: 2009)
Indication
Used to lower elevated blood glucose level
Class
Thaizolidinedione
