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Hyperthyroidism (Clinical Presentation (Increased metabolic rate,…
Hyperthyroidism
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Epidemiology
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2.7% prevalence in women, 0.23% prevalence in men
Diagnosis
Elevated T4 and T3, supressed TSH
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Pathophysiology
Thyroid antibodies are stimulated against TSH receptor >thyroid-stimulating immunoglobulins (TSIs) override regulatory mechanisms > hyperplasia of gland leading to goiter > increase synthesis of TH, T3
Treatment
Antithyroid Drugs: Methimazole, Popylthiouracil
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