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22 year old male with testicular shrinkage (Use of steroids (Receptor down…
22 year old male with testicular shrinkage
Endocrine system secretes hormones to raise and lower cell/ organ activity
Reproductive system produces sperm and egg cells
Hormonal pathway
Hypothalamus releases gonadotropin releasing hormone
Goes through hypothalamic hypophyseal portal system
Anterior pituitary releases lutenizing hormone and follicle stimulating hormone
Testes receive signal to produce their specific hormone
Use of steroids
Addiction
Negative feedback loop
Concenttration of androgens in body is high, but low testosterone in testes
Testicular atrophy
Receptor down regulation
Cells decrease their sensitivity to the hormone since it has seen it so many times, the cell decreases the amount of receptors available
Up/Down regulation
Cells increase/decrease sensitivity to hormone by changing the amount of receptors available
Low sperm count
Infertility
Low testosterone levels
Low sex drive
If steroid use ceases, testes may return to original size
May also experience withdrawal
Body has reduced its ability to produce testosterone
Testes
Testosterone
Promotes secondary sex characteristics
Develops male reproductive tissues
Estrogen
Maturation of sperm
Maintain healthy sex drive
Located in pelvic region, by upper thighs
Contained in scrotum (sac of skin)
Two oval shaped organs