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22 year old male complaining of testicular shrinkage. Admits to injection…
22 year old male complaining of testicular shrinkage. Admits to injection of synthetic, potent, anabolic steroid.
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2 Kinds of hormones
Lipid Soluble
Enter and cell and bind to intracellular receptors located in the cytosol or nucleus to form hormone-receptor complex then binds to DNA sequence called hormone-response elements.
Water Soluble
Use more complex way to stimulate target cell. Hormone binds to a plasma membrane receptor initiating signal transduction pathway
Major Endocrine glands, hormones, and functions
Pituitary Gland
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ADH
Stimulates kidneys to decrease urine output and thirst center to increase fluid intake when the body is dehydrated
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Question 2
Since androgen is diminished, a common side effect is low to zero sperm counts and low natural testosterone levels.
Question 3
Anabolic steroids facilitate the growth of skeletal muscle. They are abused for their performance-enhancing capabilities.
Question 4
When testosterone levels in the blood are artificially raised by use of anabolic steroids, the brain sends a signal to the interstitial cells in the testis to stop producing testosterone.
Hormonal Pathway
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Testes feedback on the hypothalamus and pituitary via testosterone and inhibin secretion, in a negative feedback loop to limit GnRH and gonodotropin production.